…and the inability to control them

Published 6/25/07

“So,” sez my wife, “there are going to be a lot of people oozing around here.”

“Huh?”

Seems she saw an ad from CVS or Walgreens advertising Alii, a weight-loss drug recently approved by the FDA for over the counter sales.

The full strength Alli is known as Xenical. The most memorably thing about Xenical were its commercials — not the commercials per se, but the disclaimer they contained.

It included this unforgettable warning:

“Patients may experience gas with oily discharge, increased bowel movements, an urgent need to have them and an inability to control them.”

GlaxoSmithKline even has a book for Alli users, “Are You Losing It?” One piece of advice the book gives — seriously — is that you wear dark-colored clothing when you first start taking the stuff.

Wow.

The Junkfood Science blog gives some more details.

According to Dr. Susan Norris, M.D., of the Centers for Disease Control and Prevention, despite unimpressive weight losses, “gastrointestinal adverse effects (explosive diarrhea, fecal incontinence, abdominal cramping, anal leakage and oily discharge) were common.”

And Alli doesn’t even do that much for you:

In clinical trials, those taking Alli-strength Orlistat along with dieting and exercise for a full year, lost an average of under 3 pounds more than those who were dieting and exercise alone.

Not surprising, since Alli users are required (by common sense if nothing else) to have a low-fat diet.

Here’s a screenshot from a GlaxoSmithKline video on Alli:

allivid

 

So, any questions?

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The Fray


Emily says:

And fuzzy gloves won’t help at all!

June 25th, 2007 at 7:06 PM

Randy says:

If we combined this with a diet high in Olestra, just how much would we be spending on a new tan, brown, and black wardrobe?

June 25th, 2007 at 8:23 PM

Andrew says:

Ouch. Ouch.

June 25th, 2007 at 8:41 PM

Gnomic says:

Adds a whole new twist to the phase “Ya gotta be shitting me!”

June 25th, 2007 at 8:41 PM

Andrew says:

I like the fact that people are referring to having “Alli-oops.” But can you imagine being in a restaurant?

*Splort!*
“Whoops, that was me. Sorry!”

*Blurp!*
“Heh heh, my bad.”

*Floop!*
“Oh oh, I had an Alli-oops!” [laughter]

June 25th, 2007 at 8:51 PM

Leland says:

Ewwwww…

No thanks, I’ll keep the weight.

June 26th, 2007 at 3:48 PM

Steve says:

I like how they made the symptoms pretty colors. As a graphic designer, I can bet that there was much giggling when that graphic was made:

“So, boss. What color should ’stools’ and ‘oily spotting’ be?”
“Um, brown and yellow, I guess…”
[pregnant pause]
“… and before you ask, yes, we’re getting paid double on this job.”

June 27th, 2007 at 10:56 PM

Andrew says:

I think they need better marketing people. I mean, come on — is there any circumstance in which “oily spotting” has a positive connotation?

How about the phrase my wife and I use, tongue in cheek, to describe things that happen when our son is sick: “Non-insignificant gastro-intestinal event.”

June 27th, 2007 at 11:44 PM

Speaking of Alli… says:

[...] little bit ago I reminded you all about the commercial for Xenical, the prescription form of Alli, the weight-loss pill that apparently does its work by giving you [...]

June 30th, 2007 at 11:51 PM

lionemom says:

ANAL LEAKAGE!!! Who in their right mind would EVER take an ELECTIVE “medication” that had that side effect?!?! I mean, come on! It’s the same ingredient that was used in Olestra, the same fat-absorption blocking ingredient, that’s why they have the same side effect.

Explosive diarrhea. Oh my criminy. The fact that people will take a pill that makes their rear-end leak is living proof that being overweight in the US is a social disease (obligatory disclaimer: except for the small percentage of overweight folks who have a serious thyroid condition or other condition that significantly affects their weight.) And I speak as one of those overweight people!!

BTW, the colors are part of the whole packaging of the pill. It’s all colorful with a snazzy little turquoise pill box in which you can carry your anal leakage pills.

*shudder* I’ll suffer through working out and portion control, or I’ll stay fat. No oily butt pill for me!

July 2nd, 2007 at 3:07 PM

Emily says:

When I was at GNC today they had a big promotional display up for Alli. When I commented about the potentially embarrassing side effects, the sales person told me that one customer had already returned the product.

Ick.

July 2nd, 2007 at 8:23 PM

Andrew says:

I wouldn’t have been able to help myself. I would have looked around nervously and whispered, “Is she still here?”

July 2nd, 2007 at 10:06 PM

gnomic says:

How many women smoke cigerettes to look thinner, knowing that they may die from cancer?

You think Anal leakage is bad, watch someone die from cancer. My mother, who smoked from age 12 to be thinner, was bedridden with a colostomy bag for the last 6 months of her life. She did however not smoke and lost almost 100 lbs.

Frankly I think we ought to put Alli into cigs - maybe that’ll solve the smoking problem.

July 3rd, 2007 at 12:20 PM

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